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5 Must-Have Anti-Aging Peptides for Mature Skin

Mature skin needs to be cared for in a different manner than younger skin does. When your skin gets older, the ingredients it needs to look and feel its best need to be more capable of giving your skin the boost it's going to take to revive it. But that’s ok because there are some peptides that will help you give your skin exactly what it needs.

In this article, you’re going to find the right information about the five must-have anti-aging peptides you need in your repertoire to care for your mature skin.

What Are Peptides?

Before we get into it, let’s just briefly discuss what peptides are. These little molecules are what make-up proteins in your body. They’re building blocks. Amino acids string together and form a chain that is a peptide. Then the peptides link to other peptides, and this is the protein. The protein in your body has the highest level of occurrence in collagen.

Now that you know what peptides are, you may understand that some peptides are good at helping out some of the proteins that your body uses for functioning. Good peptides can stimulate increased levels of production for functional proteins. Since collagen is one that makes our skin rejuvenate and look more youthful, then, of course, we want to promote the production of collagen in the body, especially for mature skin.


Progeline is one of the biggest buzz words in the world of skincare right now. This has an active compound in it called trifluoroacetyl tripeptide 2. This stuff packs a big punch when it comes to fighting off the visible signs of aging.

Progeline acts as an inhibitor against a bad protein called progerin. When progerin synthesizes, it causes harm to your skin cells and speeds up the aging process. By stopping the spread of progerin in the body, progeline slows the aging process down.

The other thing is that progeline helps to increase the production of collagen in your body. The collagen then firms up the skin and gives it back some of the elasticity it has lost. You’ll see less sagging of skin, less fine lines and wrinkles, and smoother younger-looking skin.


This one is a tetrapeptide, meaning it has four peptides that are strung together and connected to an acid. Relistase is very good at lifting sagging skin and preventing skin from drooping altogether.

Collagen breaks down as people get older. As we age, our bodies have a hard time replacing broken-down proteins. Relistase promotes the production of collagen to restore what’s been lost from the natural aging process. And helps the skin look and feel more elastic and tighter on the face. It also protects another vital protein, elastin. Elastin is also one that keeps skin from looking loose and droopy.

Relistase works to tighten the skin, especially on the face. Those with mature skin who want to lift the jowls off of their jawline and smooth out their necks will find this peptide to be essential to their beauty routines.


Juveleven is more about saving what you already have than it is stimulating the production of things you’ve lost. However, it can stop the premature aging that is taking place right then.

This peptide is a regulator. When it encounters something “off” in your skin cells, juveleven comes to the rescue to boost fibroblast production and save the cells that are seemingly being attached. It will delay senescence and prevent the cells from dying. Its purpose is to normalize what’s happening within the cells. This way, they can function the way they’re supposed to.


This is another tetrapeptide that’s very beneficial for anyone with mature skin. It dramatically reduces the appearance of wrinkles and fine lines. It also pulls the skin on the face tighter decreasing any sagging or drooping that is occurring.

Uplevity works by promoting collagen production, increasing elastin presence, and contributing to cell cohesion processes. This peptide has shown a lot of excellent benefits for people with aging, mature skin. It makes the skin more firm, more elastic, and gives the face back a more contoured shape. In general, people get a lifting effect from using Uplevity.


This is a tripeptide that works well as an anti-wrinkle agent. It’s a bit different than the others we mentioned. Syn-Ake decreases cell contraction in muscles. That means this one is perfect for targeting the areas where we get wrinkles from expressions we make with our faces. For instance, the crow’s feet at the corners of your eyes or the laugh lines around your mouth.

Syn-Ake is a biomimetic version of a natural peptide that’s found in the Temple Viper’s venom. It mimics the effects of Waglerin 1. Both of these work exceptionally well for smoothing out wrinkles and lines in mature skin.

The Needs of Mature Skin

There are things about the needs of mature skin that are different or at least more essential than they would be for younger skin. You have to understand your aging skin before you can truly care for it in the right way. So let’s take a minute and discuss the individual needs of your skin.

Aging skin tends to be more dried out. You need to make sure you’re moisturizing and bathing with the right products. Use warm water, creamy cleanser, and a soft cloth, and don’t wipe your skin dry. Pat it and leave a little moisture behind before you apply your moisturizer. You can also use a humidifier if the air where you live is arid.

When you do physical work in your home or your yard, wear gloves. The chemicals in cleaners and the products you use in the garden can irritate and wreak havoc your skin.

Protect your skin from the sun. Use sunscreen and wear hats that shade your face. Try to stay in the shade when you can or wear clothes that cover skin that would otherwise be exposed to the sun.

On a final note, add the peptides we mentioned in this article to your arsenal of anti-aging products. Your skin will thank you.