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Argireline Amplified Peptide Serum Booster
Argireline® Amplified Peptide Solution is the newest multifunctional anti-aging ingredient on the market.
This all-in-one anti-aging peptide is the best multifunctional peptide to make your skin glowing and look more youthful.
Sale price
€49,95
Argireline Amplified is Acetyl Hexapeptide-8, the evolution of the original Argireline peptide. You blend it into your own base at 5%, the manufacturer's maximum, for the look of expression lines on the forehead, around the eyes and between the brows.
This is a formulation ingredient, not a finished serum. Do not apply it undiluted.
What is in the bottle
INCI: Water (Aqua), Acetyl Hexapeptide-8, Sodium Benzoate
Three ingredients. Sodium benzoate is the preservative. Colorless, transparent, water-soluble solution. 0.5 oz blue glass dropper bottle.
What the supplier reports
Argireline Amplified is made by Lubrizol (Lipotec). The points below are supplier data from the Lubrizol product data sheet (published 8 Sep 2025) and the Lubrizol product page. They describe testing of the raw material, not of any blend you make at home.
- An evolution of Argireline: Lubrizol describes it as an evolution of the Argireline peptide, which it considers the first product on the market to target the look of expression wrinkles.
- Skin looks 5 years younger in 5 days (supplier claim).
- 12% average reduction in crow's feet wrinkle depth after 5 days at 5% (supplier data, Lubrizol product page).
- Helps extend the look of botulinum toxin injection results by 8 weeks: in a supplier clinical study that combined botulinum toxin injections with the peptide, the injection effect lasted about 8 weeks longer than with placebo.
- All-in-one results (supplier data): smoother looking skin surface roughness, fine lines minimized, more radiant skin, better looking firmness and elasticity, the look of increased volume, and a lifting look.
- Recovers skin appearance after facial expressions: measured by the supplier in a 3D bioprinted muscle model (in vitro).
- 99.5% natural origin content according to ISO 16128.
- Readily biodegradable (OECD 301A).
- Made in Gava, Spain. pH 4 to 5.5.
How much to add
The manufacturer's recommended range is 2 to 5%. We formulate at the top of that range, 5%. Using our house rate of 9 drops per 1% per fluid ounce:
| Concentration | Into 1 oz | Into 2 oz |
|---|---|---|
| 5% | 45 drops, 1.5 g | 90 drops, 3.0 g |
Full conversions on the serum booster chart.
How to use it
- Start with 1 oz of a water-based serum, such as our hyaluronic acid serum.
- Add 45 drops (1.5 g) of Argireline Amplified for 5%.
- Cap and shake until evenly mixed.
- Apply to clean skin morning and night, focusing on the forehead, crow's feet and the lines between the brows.
- Store the finished blend in the refrigerator.
If you have sensitive skin, patch test on the inside of the arm first, as with any new active.
Amplified or original: which one
Both are Acetyl Hexapeptide-8. The difference is the supplier's research and how much you use.
| Argireline (original) | Argireline Amplified | |
|---|---|---|
| INCI | Water, Acetyl Hexapeptide-8, Caprylyl Glycol | Water (Aqua), Acetyl Hexapeptide-8, Sodium Benzoate |
| Usage rate (maximum) | 10%, 90 drops per 1 oz | 5%, 45 drops per 1 oz |
| Reported results | In a published 2013 placebo-controlled study of 60 subjects (Wang et al.), twice-daily use for 4 weeks gave a total anti-wrinkle efficacy rating of 48.9%, vs 0% for placebo | Supplier data: 12% average reduction in crow's feet wrinkle depth after 5 days at 5%; helps extend the look of botulinum toxin injections by 8 weeks |
Pick the original if you are new to peptides or want the most formula for the money. Pick Amplified if you want the newer supplier research and a lower usage rate per batch.
Blending with other peptides
Argireline Amplified layers with Snap-8 at 10% (90 drops per 1 oz) and Syn-Ake at 5% (45 drops per 1 oz). Each works on the look of expression lines through a different route, so stacking them is not doubling up.
Storage
Refrigerate on arrival. Do not freeze. The blue glass keeps light out. The supplier's recommended retest period is 730 days from the date of manufacture.
For external use only. Cosmetic grade. Do not apply undiluted to skin. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Argireline is a registered trademark of Lipotec S.A.U., a Lubrizol company, used under licence.
Sources:
- Lubrizol, Argireline Amplified peptide solution, Product Data Sheet, published 8 Sep 2025
- Lubrizol, Argireline Amplified peptide product page
- Wang Y, et al. The anti-wrinkle efficacy of Argireline, a synthetic hexapeptide, in Chinese subjects. Am J Clin Dermatol. 2013 (PubMed 23417317)
EWG Score
The Skin Deep® ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. Learn how EWG Skin Deep scores work →
1-2
Low Hazard
3-6
Moderate Hazard
7-10
High Hazard
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Water (Aqua) Origin:
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Acetyl Hexapeptide-8 Origin:
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Sodium Benzoate Origin:
INGREDIENTS MATTER.
Customer Reviews
Questions & Answers
QI want to know which is more effective for expression lines, marionette lines, forehead lines and laugh lines Argireline amplified or Snap 8?
A
Thank you for reaching out with your question about the best options for addressing expression lines, including marionette lines, forehead lines, and laugh lines. Both Argireline Amplified and Snap-8 are excellent peptides known for their anti-aging effects, particularly in reducing the appearance of expression lines. Here’s a brief overview to help you decide which might be more suitable for your needs:
Argireline Amplified is a newer and more potent form of the original Argireline, designed to target expression wrinkles more effectively. It works by modulating the formation of the SNARE complex, thus reducing muscle contractions that lead to expression lines. Due to its enhanced action, Argireline Amplified can provide visible smoothing and softening of wrinkles and is particularly effective for areas like the forehead and around the eyes.
Snap-8 is another peptide that complements the action of Argireline by targeting different mechanisms of wrinkle formation. It also helps reduce muscle contractions but with a slightly different approach in the biochemical pathway. Snap-8 is especially useful for deeper expression lines and can be beneficial for areas like marionette lines and laugh lines.
For comprehensive results, many users find that using both peptides in conjunction can maximize anti-wrinkle benefits, as they work synergistically to reduce muscle movement and can reduce wrinkle formation from different angles. However, if you prefer to start with one, choosing might depend on which areas of your face are your priority:
- If your concern is primarily with lines around the eyes and forehead, Argireline Amplified might be the better choice due to its potent action in these areas.
- If you're more concerned about deeper lines around the mouth and lower face, Snap-8 could be more effective.
Remember, the best approach is also to consider other aspects of skincare, such as hydration, proper sun protection, and overall skin health, to complement the effects of these peptides.
Please feel free to reach out if you have any further questions or need assistance in selecting products. We're here to help you achieve the best possible results from your skincare routine.
QHow much product is in a bottle of your Argireline Amplified Peptide, and how many drops in a bottle? I was surprised it’s not listed given you offer thorough information on the ingredients and amounts to use in skincare products.
A
Each bottle is .5 ounce or 15 ml. There are approximately 300 drops in each bottle.
QHow do I add Argireline® Amplified to my current moisturizer? I use "Just Nutritive," and the pump bottle is 8 ounces. How much Argireline should I add to the bottle? And how to stir/mix? Any advice would be most appreciated. Best, Jill
A
All of our serum boosters, including Argireline Amplified come with an instruction booklet. It includes a step-by-step guide and chart so that you can quickly and easily calculate the amount of booster you will need to add. First, determine the amount needed. The manufacturer recommends using the peptide at a 5% concentration. This information can be found on the label. You can also find it on the product listing page. For an 8 ounce bottle, that would be 360 drops. Each .5 ounce bottle has approximately 300 drops. You will need to use 2 bottles or you can add a 1 ounce of the lotion to an airless pump bottle and then add 45 drops of Argireline Amplified. Second, mix until well blended. You can use a handheld blender or stir stick. For tips and tricks or to watch our "How To" Tutorial Video Series click the link.
QShould argireline plus be refrigerated
A
Yes, we recommend storing Argireline Amplified in the refrigerator. The fridge will keep it fresh for the next time you use it. You can also write the "use by" date (the date opened plus 12 months) on the label with a permanent marker.
QWhat is the difference between this Argireline Amplified and the regular one? Thanks!
A
Argireline Amplified is one of the newest anti-aging peptide. It is more powerful than the original Argireline. It is "multifunctional" and targets multiple signs of aging, not just wrinkles. If you like Argireline in your skincare products, you will love the "Amped" version.
QI want to add 10% Argireline Amplified concentration into a cream base. if the cream is 30 gm, how many drops of it would I add? How much of the peptide solution would I add to make a 10% concentration in a 30 ml cream base?
A
To make a 10% concentration in a 30 ml or 1-ounce cream base, you would add 90 drops of Argireline Amplified peptide. (90 drops equals 3/4 teaspoon plus 15 drops)
Overall rating: 4.5 / 5 from 4 reviews.
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"Always great , fabulous customer service."
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"I added this to my thick and creamy anti aging vitamin D cream along with some GHK copper peptide and it’s my new favorite day cream."
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"This is my new favorite peptide."