Argireline, Acetyl Hexapeptide 8

Anti-Aging Peptide Wrinkle-Relaxer Acetyl Hexapeptide-8, formerly called Acetyl Hexapeptide-3.

Reduce the appearance of fine lines and wrinkles while visibly smoothing your complexion with Argireline® Peptide Solution Serum Booster or Acetyl Hexapeptide-8.

Sale price $21.95
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Argireline® Peptide Solution

Argireline, Acetyl Hexapeptide 8 is the #1 Ingredient to Reduce the Appearance of Wrinkles

Argireline® Peptide Solution (Acetyl Hexapeptide-8) is a skincare ingredient that visibly reduces the appearance of fine lines and wrinkles. It is the first peptide that targets areas prone to developing expression lines. In addition, it relaxes the facial muscles to promote a smoother, less wrinkled look.

You can add our serum booster to any skincare product (serum, cream, lotion, or moisturizer) or make a custom anti-aging formula.

Just blend a small amount into your existing product for a boost, or create a custom anti-aging serum. An easy-to-follow instruction guide and chart are provided with the purchase.

Our table takes the guesswork out of how much to add. Argireline® Peptide Solution is one of our favorite ingredients to help restore the skin's smooth, youthful appearance.

Anti-Aging Neurotransmitter Peptide

Are you looking for an alternative to Botox®? That won't cost an arm and a leg? One that doesn't require a visit to the dermatologist, medical spa, or cosmetic surgeon's office?

Argireline® Peptide Solution (Acetyl Hexapeptide-8) from Skin Perfection has been called "Botox® in a bottle." Dr. Oz has recommended it as a viable alternative to muscle-relaxing injections like Botox® and Dysport.

Facial Muscle Memory

How does the Argireline® Peptide Solution work? It is made up of a strand of six amino acids. This hexapeptide works by inhibiting the activity of neurotransmitters. In addition, it inhibits neurotransmitters in the area where it is applied.

In other words, it relaxes your facial muscles the same way that Botox does but without the injections or the expensive bill.

By doing this, the Argireline® Peptide Solution can significantly and visibly reduce the appearance of fine lines and wrinkles around your nose, mouth, eyes, and brow.

Affordable Treatments for Fine Lines and Wrinkles

Have a serum, lotion, or moisturizer that you like? By adding a 2-10% concentration of Argireline® Peptide Solution to it, you'll find that it works significantly better in the anti-aging department.

Want to make skincare products at home? You can add the Argireline® Peptide Solution to them and create custom lotions, serums, moisturizers, or creams to suit your personal skincare needs.

We include a detailed instruction guide and chart with each purchase, so you'll know how much Argireline® Peptide Solution can add to any formula or product for the perfect boost. Argireline® Peptide Solution is one of the most potent and effective anti-wrinkle ingredients available.

We love it, and we think you will, too! So purchase a bottle today and see incredible results and gorgeous, youthful skin with any product you add it to!

Argireline, Acetyl Hexapeptide 8 Targets

Argireline® Peptide Solution is highly effective for battling the signs of aging on your face. Over time, as you smile, frown, squint, or make other facial expressions. You notice fine lines and wrinkles appearing (and growing deeper) around your mouth and nose smoothed.

You'll see the worry lines between your eyebrows-the 11's, and crow's feet around the corners of your eyes fading. In addition, horizontal creases that appear under the eyes or around the mouth will be visibly reduced.

Argireline® Peptide Solution targets all of these signs of aging and virtually turns back time on your face. Add Argireline, Acetyl Hexapeptide 8 to your favorite rejuvenating products for:

  • Anti-aging
  • Anti-wrinkle
  • Expression lines
  • Fine lines and wrinkles

Clinical Studies

First introduced in 2001, Argireline peptide is one of the most recognizable cosmetic ingredients. It has been shown that Argireline improves the appearance of fine lines and wrinkles in just one week.

Participants of this clinical study used a 2% concentration. As a result, depth decreased by an average of 15.9%, while volume improved by 20.6%.

Other studies have shown a decrease in developing dynamic folds, including reducing skin roughness.

Also Found In

Major cosmetics and skincare brands have discovered the incredible effects of Argireline® Peptide Solution. You'll find these products in department stores and cosmetics shops:

  • DDF Bio-Molecular Firming Eye Serum
  • Desert Essence Age Reversal Face Serum
  • Revlon Age-Defying Foundation

Reduce Appearance of Wrinkles with Argireline

Don't spend a lot of money on these and other products with Argireline® Peptide Solution. They'll often have lower concentrations than you want, and you'll pay top dollar for them. Instead, add Argireline® Peptide Solution to skin care products for excellent results at a much lower price.

EWG Score

The Skin Deep® ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. Learn more
1-2 Low Hazard
3-6 Moderate Hazard
7-10 High Hazard

  • Water Origin:
  • Acetyl Hexapeptide-8 Origin:

What is Argireline?
Argireline is the most trusted anti-aging peptide. It is one of the most popular, widely used, and reputable anti-wrinkle peptides used in the skincare industry.
Is Argireline a good alternative to botox?
Argireline is considered one of the best botox alternatives! Argireline relaxes your expression line facial muscles whereas Botox paralyzes those muscles. Both result in a reduction of fine lines and wrinkles.
Does this product need to be refrigerated?
We recommend placing Argireline in your fridge to keep it fresh for the next time you need it.

INCI: Water (and) Acetyl Hexapeptide-8

Recommended Usage Rate: 2-10%

Place in the refrigerator upon arrival.

Color: Colorless

Appearance: Clear liquid

Solubility: Water-soluble

pH: 3.0-6.0

Scent: No fragrance, unscented

Storage: Store in a cool dark place

Shelf-life: 12 months after opening

Country of Origin: Spain

Raw Material: Plant-based

Animal Testing: Cruelty-free


Vegan: Yes

CAS: 616204-22-9

HS Code: 3504.00

Acetyl Hexapeptide-8 is a peptide that targets the formation of wrinkles by reducing contractions. It also helps reduce the appearance and depth of expression lines.

We recommend a 2-10% concentration when mixing the Argireline® Peptide Solution into any existing skincare product or adding it to your recipe at home. With your current product, blend the Argireline® Peptide Solution into the product until you have a uniform mixture.

If you're creating a lotion, serum, or moisturizer at home, be sure to add your Serum Booster drops during the water phase.

For a 10% concentration of Argireline in a 1-ounce skincare product, bulk base, or formula, add 90 drops.

For a 2% concentration of Argireline in a 2-ounce skincare product, bulk base, or formula, add 36 drops.

Included is our product instruction guide on how to add serum boosters to your formula. Argireline® Peptide Solution works excellent with other anti-wrinkle peptides. For example, Snap-8™ Peptide, Inyline® Peptide, and Syn®-Ake are great candidates. Using a blend of peptides can maximize their skincare benefits.

Formulation: Add transparent liquid at the end of the formulation. You can also add it to the water phase. This peptide is super easy to incorporate. It is a clear liquid that has the consistency of water. It is fragrance-free and will not change the product scent.

When used at high concentrations, as with all ingredients, the formula you are adding it to may get thinner.

Size: .5 ounce of Argireline® Peptide Solution NP (non-paraben), protected from light by a blue glass bottle with a dropper.

Place in the refrigerator upon arrival.

Argireline® Peptide Solution is an anti-wrinkle active used in serum making. Do not apply directly to the skin.

Sample Recipes

If you're not sure how to add a serum booster to one of your favorite skincare products, you might be nervous about trying it for the first time. We're here for you! We've made a helpful video to walk you, step-by-step, through the process of adding a serum booster to an existing product.

Are you feeling adventurous? Making skincare products is fun and a lot easier than you might think! Check out our recipe for a supercharged anti-aging serum with an Argireline boost or how to make your own Argireline Peptide face cream.


  • Anti-Aging Day and Night Moisturizers
  • Anti-Aging Face Serums
  • Body Butters
  • Eye Creams and Gels
  • Facial Mists, Toners, or Astringents
  • Highly Concentrated Back Bar Facial Treatments
  • Hyaluronic Facial Serums
  • Lotions and more!

Do not directly apply to your skin. Instead, this product should be added to a formulation at the recommended usage rate.

For external use only, all products are cosmetic grade.

The Food and Drug Administration has not evaluated the statements contained herein. This product is not intended to diagnose, treat, cure, or prevent disease. Always consult with your professional skincare provider.

California Prop 65 Statement: The following statement is made to comply with the California Safe Drinking Water and Toxic Enforcement Act of 1986. This product is not known to the State of California to cause cancer, birth defects, or other reproductive harm.

Argireline® Peptide Solution is a registered trademark of Lipotec S.A. or its affiliates.

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Slide 1:
Anti-Aging Solutions
Rejuvenate with Youth-Boosting Argireline® Peptide

Slide 2:
Video of what it is.
Boost any skincare product's effectiveness. Simply add 90 drops of Argireline® Peptide to a 1-ounce base, custom formula or existing product for a 10% concentration.

Slide 3:
Highest Quality Anti-Aging Peptides for Making Skincare
Reduce the appearance of fine lines and wrinkles and visibly smooth your complexion.

Slide 4:
Benefits of Argireline® Peptide -
Expression lines
Fine lines and wrinkles

Slide 5:
Skin Perfection Logo
Supercharge your skin with the highest quality anti-aging peptides.

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Discover the anti-aging ingredient for wrinkles that I swear by.
Acetyl Hexapeptide-8

Anti-Aging Peptides For Lotion Making

Customer Reviews

Questions & Answers

Have a Question?

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  • How do I add this to a 1.7 ounce moisturizer?

    For a 10% concentration added to a 1-ounce of a base, you would need to add 1 1/2 teaspoons plus 11 drops.

  • Can I add Argireline to Jojoba oil?

    Argireline is a water-based anti-aging peptide. It can be added to our Ultra Hyaluronic Acid or another serum base. It should not be added to an oil-based product as water can't combine with oil unless an emulsifier is used.

  • Is this the same as Acetyl Hexapeptide 3?

    Acetyl Hexapeptide-3 is an old INCI name. Argireline now is called Acetyl Hexapeptide-8.

  • I am making a DIY serum. What other ingredients should I use with Argireline?

    Ask your self what your goals are. If you are looking to reduce the appearance of wrinkles and want to make a DIY powerhouse serum, add Snap-8, Inyline, and Syn-Ake. If you want to firm a sagging jawline, add Uplevity, Pepha Tight, and Relistase. For more volume and supple skin, consider Hyaluronic Acid and Syn-Coll. You can also check out our peptide guide at to help locate the best peptides to use.

  • How does this compare to the Ordinary 10% Argireline Solution?

    The Argireline Peptide Serum Booster needs to be added to any skincare product, base, or formulation.

    You can easily create a clean beauty product by adding a 10% concentration (the same that the Ordinary Solution uses) to a base of Hyaluronic Acid. You will make a formula that has the same 10% concentration as the Ordinary but without additional chemical additives or preservatives such as Phenoxyethanol.

  • Do you ship to Australia?

    Yes! We ship worldwide including Australia.

    Shipping quotes are given at checkout.

    Please view our shipping guide for the latest information about any country shipping delays and order minimums.

    All international orders may have additional duties, taxes, customs, or other fees associated with purchase. These taxes are the customer's responsibility.

  • Can I use Argireline with Vitamin C?

    Argireline Peptide is compatible with many different ingredients including Vitamin C.

  • I make a facial moisturizer. It is lotion/moisturizer consistency. The only two ingredients are tallow (rendered beef fat) and jojoba oil. Since this is moisturizer consistency can it be mixed in? It would be able to be uniformly mixed.

    Yes, the Argireline Peptide Serum Booster can be added to your moisturizer! We recommend using a 10% concentration at the end of formulation.

  • What would be similar to this (natural botox like effect) that can be used in a serum that is completely made with oils and no water?

    Unfortunately, there are none. Peptides are "hydrophilic" or water-loving. Your best bet is to use an emulsifier to incorporate the peptides or add to a base of Hyaluronic Acid.

    You can find some plant extracts that are oil-soluble however, they will have water in them and an emulsifier.

  • Can I just use pretty much all of the serums together to get all effects, or do some not go with others?

    Yes, you can combine multiple Serum Boosters together. There is no right or wrong number. Just make sure that you are not using Copper Peptide with Vitamin C.

  • Can this be mixed with just filtered water? I would make only 4-5 days of Argireline-water solution at a time and keep in the fridge to prevent any microbial issues. Also, how long should Argireline ideally be allowed to sit and absorb into skin before applying other products (such as sunscreen) on top?

    Yes, you can use Argireline Peptide with water.

    You can apply additional products, including sunscreen, as soon as the Argireline solution is dry.

  • Can Argireline Acetyl Hexapeptide 8 be used alone prior to putting on niacinamide & hyaluronic serum?

    Argireline is an anti-aging ingredient and needs to be mixed prior to use. You can add it to your Niacinamide and Hyaluronic Acid Serum to give it a boost.