Dermafill Wrinkle Filler

Hydrating Phospholipids + Glycoproteins

Adipofill (Adipofill' in) is a wrinkle filler that targets fat deposits on the upper cheekbones for a plumper, more lifted, and refreshed appearance.

Sale price $29.95
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Fill Wrinkles with Dermafill

A recommended usage rate of 1-3%

Our Dermafill comes in a .5 fluid-ounce blue glass dropper bottle.

Are you tired of seeing pockets on the cheeks? Are under-eyes becoming hollow? Brow's beginning to droop? At the same time, are you hesitant about injections and expensive treatments from the dermatologist?

If you're looking for a natural, effective solution, and won't require a trip to see the dermatologist, try Dermafill Wrinkle Filler.

What makes Dermafill better than other wrinkle fillers? First, it contains Adipofill-in™, a revolutionary wrinkle filler with patented L-ornithine amino acid in lonesomes.

These amazing, natural ingredients plump nasolabial lines, lift the apples of your cheeks and fill in the hollows under your eyes.

Dermafill also lifts sagging brows for a more refreshed and rejuvenated look too.

Now available in our DIY collection, you can add this beneficial anti-aging booster to your favorite moisturizer, serum, or night cream. You can also make natural skin care products more potent than name-brand products at a fraction of the cost!

Pick up a bottle of Dermafill today and see all of the fantastic ways you can boost your skincare regimen with natural ingredients at home. Product instructions are included with each order, and you can find helpful recipes and tutorials on our blog, too!

Purchase a .5-ounce bottle of Dermafill, and you'll see significant improvements in the anti-aging effects of any product you add it to. In addition, at a 1-3% concentration, you'll only need a few drops for most formulas.

This will give you the best results at a much lower cost than purchasing expensive designer products.


  • Expression lines
  • Sagging cheekbones
  • Under-eye circles
  • Sagging brow

Dry Shampoo and Essential Oils

When adding Dermafill to an existing product, we recommend 1-3% usage. Do you have a favorite serum, moisturizer, or cream that you like but could use as a rejuvenating boost? Then, add a few drops of Dermafill.

Or, if you're comfortable making custom skincare products, add them to the water phase of your formula. Adipofill-in is a creamy, light yellow in color and aqueous solution.

After opening the bottle, be sure to refrigerate any unused contents to keep your Dermafill fresh and potent for your subsequent use. Because we do not add preservatives or additional inactive ingredients, keeping Dermafill at room temperature is not recommended.

The blue tint of the bottle preserves its components from the harmful effects of light exposure. Also, refrigeration will maintain the product's effectiveness for as long as needed.

Also Found In:

Dermafill's primary active ingredient, Adipofill-in™, is also found in these name-brand skincare products available at department stores and cosmetics boutiques:

  • Eva Marée Lip Maximizer
  • Lucas Meyer La Spirit Cream
  • Ageless Advanced Age-Defying Serum by Skin Perfection


  • Eye Creams
  • Anti-aging Serums
  • Moisturizers
  • Breast Enhancement Creams

EWG Score

The Skin Deep® ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. Learn more
1-2 Low Hazard
3-6 Moderate Hazard
7-10 High Hazard

  • Water Origin:
  • Propanediol Origin:
  • Ornithine Origin:
  • Phospholipids Origin:
  • Glycolipids Origin:

What problems does Dermafil target?
Dermafil can help with expression lines, sagging cheekbones, under-eye circles, and a sagging brow.
What is Dermafil?
Also known as Adipofill (Adipofill'in), it is a wrinkle filler that targets fat deposits on the upper cheekbones for a plumper, more lifted, and refreshed appearance.
Does this product need to be refrigerated?
We recommend placing Dermafil in your fridge to keep it fresh for the next time you need it.

INCI: Water (and) Propanediol (and) Ornithine (and) Phospholipids (and) Glycolipids

Recommended Usage Rate: 1-3%

Place in the refrigerator upon arrival.

Color: Off-white to pale yellow

Appearance: Liquid

Solubility: Water soluble

pH: 4.0-6.0

Scent: No fragrance, unscented

Storage: Store in a cool, dry place at temperatures lower than 25°C.

Shelf-life: 12 months after opening

Country of Origin: Germany

Raw Material: Plant-based

Animal Testing: Cruelty-free


Vegan: Yes

CAS: 504-63-2/70-26-8/8002-43-5

HS Code: 3504.00

Additional Instructions: Add 1-3% into a base formula below 40°C, and stir until well blended.

Instead of paying top dollar for these products, which often don't have the same concentrations or potency for the best results, why not create your own serums, creams, plumpers, and moisturizers?

You can learn how to make many of these products in your home in our DIY section or follow the instructions below.

For a 3% concentration of Dermafil in a 1-ounce skincare product, bulk base, or formula, add 27 drops.

For a 1% concentration of Dermafil in a 2-ounce skincare product, bulk base, or formula, add 18 drops.

Adipofill-in® is a cosmetic active used in our Dermafill. It is for making lotions and potions. Do not apply directly to the skin.

Sample Recipe:
1-ounce Base of Hyaluronic Acid
27 drops of Adipofill-in

You can even add Dermafill to our homemade aloe vera gel recipe. You'll get all of the rejuvenating plus the antioxidant powers of aloe vera gel with the added anti-aging boost of topical treatment in a bottle.


  • Anti-Aging Face Creams
  • Anti-Aging Serums
  • Day and Night Moisturizers
  • Firming Body Lotions
  • Highly Concentrated Back Bar Facial Treatments
  • Hyaluronic Facial Serums and Gels
  • Make-up Including Foundation
  • Tightening Eye Creams, Eyelash, Eyebrow Formulas, and more!

For external use only, all products are cosmetic grade.

Use care when applying near the mouth and eyes, and avoid contact with broken or irritated skin. Keep out of reach of children.

Do not directly apply to your skin. Instead, this product should be added to a formulation at the recommended usage rate.

The Food and Drug Administration has not evaluated the statements contained herein. This product is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional skincare provider.

California Prop 65 Statement: The following statement is made to comply with the California Safe Drinking Water and Toxic Enforcement Act of 1986. This product is not known to the State of California to cause cancer, birth defects, or other reproductive harm.

Intro music

Slide 1:
Anti-Aging Solutions
Rejuvenate with Youth-Boosting Dermafill

Slide 2:
Video of what it is.
Boost any skincare product's effectiveness.
Simply add 27 drops of Dermafill to a 1-ounce base, custom formula, or existing product for a 3% concentration.

Slide 3:
Highest Quality Anti-Aging Ingredients for Making Skincare
Adipofill is a wrinkle filler that targets fat deposits on the upper cheekbones for a plumper, more lifted, and refreshed appearance.

Slide 4:
Dermafill Targets -
Expression lines
Sagging cheekbones
Under-eye circles
Sagging brow

Slide 5:
Skin Perfection Logo
Supercharge your skin with the highest quality anti-aging peptides.

Outro video


Achieve smoother, hydrated skin with our advanced topical wrinkle filling treatment.
Amino Acids + Glycolipids + Phospholipids + Propanediol

Customer Reviews

Questions & Answers

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  • Does this also work as a penetration enhancing product? I was considering the booster meant to enhance other ingredients but I\'d rather purchase one that helps fill in skin and help with penetrating.

    Yes, L-ornithine is an amino acid obtained from vegetable starch, encapsulated in an Ionosome™. The encapsulated Ionosome™ is the enhancer that helps ingredients work better when applied topically.

  • Is there a certain PH the filler works best with?

    For the best results, use a PH between 4.5-6.0.

  • Would this product work mixed into a single oil ingredient, like avocado oil? Or is it better to mix it into a humectant like aloe vera? I didn't have results with this a few years ago when I mixed it into a butter, oil-type moisturizer.

    Dermafill is a water-based anti-aging ingredient. It needs to be mixed into a base that consists of mainly of water such as aloe, hydrosols, Hyaluronic Acid, etc.

  • I have ordered Pepha Tight Serum Booster and Uplevity. Can Dermafill Wrinkle Filler be mixed with these two fillers and Matrixyl Synthe 6, Wrinkle Firming Filler?

    Yes, the Serum Boosters can be used interchangeably. You can add Dermafill, Pepha Tight, Uplevity, and Matrixyl Synthe-6 to your formula.