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Syn Ake

EWG Rating
Syn-Ake Skincare Ingredient Rating

Scientific Name: {Di-peptide Diaminobutyroyl Benzyl-amide Di-acetate}
Common Name: {Syn-Ake or Syn Ake}

While some anti-aging ingredients only relax wrinkles or tighten skin, Syn-Ake does both. Many people have products with peptides that only relax wrinkles because they don't quite smooth areas. Smoothing is not a problem with Syn-Ake wrinkle smoother peptides.

It not only works on lines caused by facial muscle cell contractions. (You know those 11's, the frown lines in between the brows) But also provides a smoother, firming lift on creases.

This peptide is inspired by nature. It is based on the Temple Viper’s venom. It's asynthetic tripeptide that mimics the effects of the venom.While it sounds poisonous and dangerous to use, it's not. It's an amino acid sequence or peptide (protein) with some fantastic benefits. SYN®-AKE is based on the principle of the Waglerin-1 component. 

This tripeptide works magic on your skin. It has a powerful freezing effect. It can help delay the onset of early aging and decrease the depth of wrinkles in mature complexions. It is an all-around must-have if you experience expression lines around the mouth, laughter, forehead, crow's feet, and lip lines. 

Most of us don't commonly think of venom regarding skincare. But it does have some significant advantages. The cosmetic ingredient paralyzes muscles, in turn, smooths them out so that they don't contract. Over time, our facial muscles begin to "remember" their place — the muscles contract time after time. When this happens, the muscle is tight. It starts to create a crease, which eventually leads to a making a wrinkle. These are called mimic wrinkles. They can be reversed by nerve impulses that send messages to the ACh receptors. The muscular nicotinic acetylcholine receptor (mnAChR) is blocked, keeping ion channels closed, and the sodium ion (Na+) is not absorbed. 

Syn-Ake relaxes the muscles. It also helps the facial muscles to forget their placement and then firms up the facial area, creating a smoother, unwrinkled space. It's highly effective when used in a 5% concentration, and with continued, it has the best cumulative effects. You will love the change you see as your face begins to return to its rightful place. You'll love that you can still enjoy life and laugh without having to worry about your face wrinkling like a prune.

Some anti-aging ingredients provide instantaneous results. However, you must use the cream to maintain those results, Syn-Ake delivers instant gratification, and then those results are stacked upon with continued use.

As the skin ages, most women begin to see both wrinkles due to muscle contractions under the skin and sagging skin. Repeated use of muscles creates wrinkles on the surface of the skin. Over time, those muscles become contracted perpetually, and the fine lines become permanent.

Simultaneously, the face loses its inherent elasticity, and women begin to see the drooping skin around the eyes, especially around the chin and neck. In the past, you could solve only one of these problems with a single ingredient. Now, DSM provides an anti-aging solution with a product that contains Syn-Ake, a patented ingredient from the Swedish company Pentapharm LTD.

Syn-Ake Wrinkle Smoothing Peptide

It both tightens the skin look and reduces the muscle contractions that cause crow’s feet, parentheses around the mouth, and forehead lines. Working to inhibit the transmission of impulses that cause those muscles to tense up begins to smooth and relax the look of fine lines and wrinkles.

Typically, this would cause there to be more skin to sag away from the face. However, this unique peptide also encourages elastin and collagen to return to their normal levels. More elastin and collagen produce younger-looking faces. You will see your complexion tighten with continued use, jowls lifted, and more supple, hydrated, and plump skin.

Studies have shown that using Syn-Ake for four weeks and twice a day can smooth the look of wrinkles by more than 50%. This active peptide is exceptionally effective and has been tested thoroughly. Compared to measures like Botox, it can provide similar results without even having to get an injection.

Many women have begun using a wrinkle-relaxing serum-infused product with Syn-Ake instead of resorting to Botox, as it is safer, effective, and eliminates the need for needles. Anti-Wrinkle Injection for Crow's Feet with Syn-Ake

Wrinkle Injections VS. Topicals

The most common anti-wrinkle injection is Botox. Many other brand name injectables are Dysport or Bolotero. While these are mild alternatives to Botox, they are not as strong.

Treatment areas include the 11's - the lines between the brows, sometimes referred to as furrows — forehead lines, crow's feet, and the fine lines in the under-eye hollows.

Anti-wrinkle injections instantly remove wrinkles. The downside is that they are expensive, require maintenance every two to three months, and toxins are injected into your facial muscles.

Facial fillers treat volume loss and minimize wrinkles instantly. Hyaluronic Acid is the most commonly used ingredient. It is a natural material found in the skin, is injected into the dermis.

The result is a wrinkle-free face. Many injections take 5 to 10 years off of your appearance immediately. They can also change the shape of your face. Many treatments "fill" creases and lines, but they even can restore volume and enhance the shape of the face. This can be in the form of a non-surgical lift.

Dermal Facial Fillers Target

  • Lips lines
  • Nasolabial folds, the marionette lines around the mouth
  • Cheeks
  • Under-eye hollows
  • Eyebrows
  • Bunny lines, the horizontal crease on your nose below your forehead
While dermal facial fillers are more natural as they contain hyaluronic acid, some wrinkle-fillers are not.

The most popular brand, Juvederm, is made from Hyaluronic Acid. Radiesse is an example of a wrinkle-filler that uses calcium microspheres to enhance your body's own collagen production and treat volume loss. They do have side effects such as bruising and do require downtime. Fillers tend to last longer than anti-wrinkle injections but are even more costly.

Topicals are the safest and least expensive option to treat the appearance of wrinkles, fine lines, and creases. There is no downtime and no costly trips to the dermatologist. Using a topical treatment twice a day can help minimize wrinkles.

Syn-Ake does have a cumulative effect. You can achieve maximum benefits in 30 days. You won't be disappointed, as studies have shown this tripeptide to minimize wrinkle-depth by 30%. Obtain a youthful appearance with the use of topicals. Peptides are the driving force behind the anti-aging benefits. It is best to use a combination of peptides for the best results.

Clinical studies have shown that anti-aging peptides such as Matrixyl 3000 can help you look 5 to 10 years younger in as little as two months when used twice a day. Using a combination of Matrixyl 3000, Syn-Ake, Pepha Tight, and Syn-Coll is one of the best topical serums for a younger-looking natural appearance.

Ingredients:
INCI name (active): Glycerin, Aqua, Dipeptide Diaminobutyroyl Benzylamide Diacetate.
Molecular Weight: Less than 500 Daltons
Preservative-free, Paraben-free, Vegan-Friendly, Safe for Topical Applications
Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266942/
https://pubchem.ncbi.nlm.nih.gov/compound/Syn-ake
https://www.dsm.com/personal-care/en_US/products/skin-bioactives/syn-ake.html

About the Author

Kari Thomas wrote this article.

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