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5 Must-have Anti-Aging Peptides

5 Must-Have Anti-Aging Peptides for Mature Skin

Top Anti-Aging Peptides to Help you Survive Winter Weather

Mature skin needs to be cared for differently than younger skin. As your skin ages, its need for nourishment changes. Your skin will require high-quality ingredients to look healthy and radiant. This is where peptides come into play - as the right ones can help support your skin, always be at its best.

When your skin gets older, the ingredients it needs to look and feel its best need to give your skin the boost it will take to revive it. But that’s ok because some peptides will help you give your skin exactly what it needs.

In this article, you’re going to find great information about the five must-have anti-aging peptides you need in your repertoire to care for your mature skin.

It truly is never too early or too late to start with the right skincare regimen.

What Are Peptides?

Before we discuss some of the key peptides, let’s briefly talk about what peptides are. Peptides are building blocks that make up the proteins in your body. Essential amino acids string together and form a chain that is a peptide. Then the peptides link to other peptides, and this becomes a protein.

Much of the protein in your body is highly concentrated in collagen, one of the main components providing structure to skin, blood vessels, and organs.

Now that you understand the role of peptides, it will become clearer that some of these peptides can support the role of functional proteins in your body. When a peptide consists of a short chain of amino acids, it can penetrate the skin's superficial layers.

Once these peptides penetrate, they can send signals to the cells to support healthy function. These useful peptides can help improve the production of healthy protein, such as collagen. When the levels and structure of collagen in your skin is optimal, your skin appears healthy and rejuvenated.


Progeline is one of the most important buzz words in the world of skincare right now. This has an active compound in it called Trifluoroacetyl Tripeptide 2. This stuff packs a big punch when it comes to fighting off the visible signs of aging.

Progeline modulates a protein called progerin. When progerin synthesizes, it causes harm to your skin cells and speeds up the aging process. By inhibiting progerin, the collagen can remodel and reduce the appearance of fine lines, wrinkles, and sagging skin. The result is firmer, smoother, and younger-looking skin.


Relistase is a tetrapeptide, meaning it has four peptides strung together and connected to an acid. Relistase is very good at lifting sagging skin and preventing the skin from drooping altogether.

Collagen diminishes and loses its structure over time and from many environmental influences. As we age, our bodies have a hard time replacing broken-down proteins. Relistase promotes the production of collagen to restore what’s been lost from the natural aging process. And helps the skin look and feel more elastic and tighter on the face.

It also protects another vital protein, elastin. Elastin is also one that keeps the skin from looking loose and droopy. Once elastin is gone, we have no way to rebuild it, so it is essential to protect the elastin you have.

Relistase works to tighten the skin, especially on the face. Those with mature skin who want to lift the jowls off their jawline and smooth out their necks will find this peptide essential to their beauty routines.


Juveleven is more about saving what you already have than it is stimulating the production of things you’ve lost. However, it can stop the premature aging that is taking place right then.

This peptide is a regulator. When it encounters something “off” in your skin cells, juveleven comes to the rescue to boost fibroblast production and save the cells that are seemingly being attacked. It will delay senescence and prevent the cells from dying. Its purpose is to normalize what’s happening within the cells. This way, they can function the way they’re supposed to.


Uplevity is another tetrapeptide that’s very beneficial for anyone with mature skin. It dramatically reduces the appearance of wrinkles and fine lines. It also pulls the skin on the face tighter decreasing any sagging or drooping that is occurring.

Uplevity works by promoting collagen production, increasing elastin presence, and contributing to cell cohesion processes. This peptide has shown a lot of excellent benefits for people with aging, mature skin. It makes the skin more firm, more elastic, and gives the face back a more contoured shape. In general, people get a lifting effect from using Uplevity.


Syn-Ake is a tripeptide that works well as an anti-wrinkle agent. It’s a bit different than the others we mentioned. Syn-Ake decreases cell contraction in muscles. That means this one is perfect for targeting the areas where we get wrinkles from expressions and facial movements. For instance, the crow’s feet at the corners of your eyes, the frown lines between your brows, or laugh lines around your mouth.

Syn-Ake is a biomimetic version of a natural peptide that’s found in the Temple Viper’s venom. It mimics the effects of Waglerin 1. Both of these work exceptionally well for smoothing out wrinkles and lines in mature skin.

It obviously needs a consistent, repeated application to maintain its effect.

The Needs of Mature Skin

There are things about the needs of mature skin that are different or more essential than those for younger skin. You have to understand your aging skin before you can genuinely care for it in the right way. So let’s take a minute and discuss the individual needs of your skin.

Aging skin tends to be more dried out. You need to make sure you’re moisturizing and bathing with the right products. Use warm water, creamy cleanser, and a soft cloth, and don’t wipe your skin dry. Pat it and leave a little moisture behind before you apply your moisturizer. You can also use a humidifier if the air where you live is arid.

When you do physical work in your home or your yard, wear gloves. The chemicals in cleaners and the products you use in the garden can irritate and wreak havoc on your skin.

Protect your skin from the sun. Use a physical sunscreen and wear hats that shade your face. Try to stay in the shade when you can or wear clothes that cover skin that would otherwise be exposed to the sun.

On a final note, add the peptides we mentioned in this article to your arsenal of anti-aging products. Your skin will thank you.