Key Product Ingredients
Key Ingredients in Skin Perfection Products, by Skin Goal
Skin Perfection products are built around a short list of key ingredients: amino acid sequences (peptides) for the look of lines and firmness, humectants and barrier lipids for hydration, vitamins and antioxidants for a brighter, more even look, and gentle botanicals and plant oils for comfort. This page groups those ingredients by what they do, so you can choose by goal rather than by name. Each link opens the glossary entry, with usage rates, sources, and the products that contain it.
Looking for a specific ingredient? Use the A to Z ingredient glossary.
Smooth the Look of Expression Lines
Amino acid sequences that are often compared to "Botox in a bottle" because they target the look of lines that form when you frown, squint, or smile. They are topical cosmetics, not injections, and they work on the look of the skin surface over weeks of daily use.
Support the Look of Firmness and Fewer Wrinkles
Signal peptides, copper peptide, and collagen-support ingredients for skin that looks thinner, looser, or more lined with age.
- Matrixyl 3000
- Matrixyl Synthe'6
- Syn-Coll (Palmitoyl Tripeptide-5)
- Syn-Tacks (Palmitoyl Dipeptide)
- Copper Peptide (GHK-Cu)
- Pepha-Tight
- Relistase
- Regu-Age
- Epidermal Growth Factor (EGF)
- Collagen
- Matrikins
- DMAE
Hydrate and Support the Skin Barrier
Humectants draw water into the outer layer, and barrier lipids help hold it there. These suit every skin type and are the base of most routines.
- Hyaluronic Acid
- Natural Moisturizing Factor (NMF)
- Ceramides
- Phospholipids
- Beta Glucan (Oat Straw)
- Aloe Vera
- Comfrey Root and Allantoin
- Shea Butter
Brighten and Even the Look of Skin Tone
Ingredients for dullness and the look of dark spots. Pair them with daily sunscreen, because new sun exposure undoes visible progress.
- Vitamin C
- Niacin (Vitamin B3)
- Alpha Arbutin
- Kojic Acid
- Licorice
- Alpha Hydroxy Acids (AHAs)
- Glycolic Acid
- Lactic Acid
Antioxidant Support
Antioxidants help skin cope with the free radicals created by sunlight and pollution. They work best in the morning, under sunscreen.
- Vitamin E
- Green Tea
- Resveratrol
- Coenzyme Q10 (CoQ10)
- Idebenone
- Edelweiss Extract
- Pycnogenol (Pine Bark)
- Pomegranate
- Superoxide Dismutase
Refine Texture and Renewal
For rough texture and the look of fine lines. Introduce these slowly, at night, and use sunscreen in the morning.
Under-Eye Area
Ingredients chosen for the look of dark circles, puffiness, and crepey skin around the eyes.
Calm Sensitive-Feeling Skin
Gentle botanicals for skin that looks pink or feels easily irritated. Patch test first and start at the lowest rate.
Nourishing Plant Oils for Dry Skin
Plant oils soften and help seal in moisture. Apply them as the last step at night, or blend a few drops into moisturizer.
- Jojoba Oil
- Argan Oil
- Evening Primrose Oil
- Borage Oil
- Sea Buckthorn Berry
- Tamanu Oil
- Rice Bran Oil
- Avocado
Peptide Serum Booster Rates at a Glance
If you add serum boosters to your own base, these are the rates Skin Perfection uses, at the highest manufacturer rate. Our house drop rate is 9 drops = 1% per fluid ounce.
| Ingredient | Main goal | Skin Perfection rate | Per fluid ounce |
|---|---|---|---|
| Argireline | Look of expression lines | 10% | 90 drops |
| Snap-8 | Look of expression lines | 10% | 90 drops |
| Syn-Ake | Look of expression lines | 5% | 45 drops |
| Matrixyl 3000 | Look of wrinkles and firmness | 8% | 72 drops |
| Syn-Coll | Look of wrinkles and firmness | 3% | 27 drops |
| Syn-Tacks | Look of firmness | 3% | 27 drops |
| GHK-Cu copper peptide powder | Look of firmness and smoothness | 1% | 1 g per 100 ml |
If your skin is sensitive, patch test on the inner arm for 24 hours and start at the lowest rate in the manufacturer's range, then work up. Our guide on how to add a serum booster shows the method, and the full range is in Anti-Aging Peptides.
What This Means for Your Routine
- Pick one goal at a time. Start with the concern that bothers you most, and choose one or two ingredients from that group.
- Keep the base steady. A gentle cleanser, a hydrator such as hyaluronic acid, a moisturizer, and broad-spectrum SPF 30 or higher every morning support every goal on this page.
- Do not stack too many actives. The American Academy of Dermatology notes that using too many products, especially several anti-aging products at once, can irritate skin. Use exfoliating acids and retinol on different nights.
- Give it time. Studies cited in our glossary, such as the 2-month Matrixyl 3000 supplier study, measure results over weeks rather than days, so judge results after at least 8 weeks of daily use.
For a deeper dive into peptides, read Peptides in Skincare: A Cosmetic Formulator's Complete Guide.
Frequently Asked Questions
What are the key ingredients in anti-aging skincare?
The most common are sunscreen filters, antioxidants such as vitamin C, hydrators such as hyaluronic acid, retinoids such as retinol, and peptides such as Matrixyl 3000 and Argireline. Each targets a different part of how skin looks as it ages. A simple routine uses one from each group rather than many at once.
Which skincare ingredients work well together?
Hyaluronic acid pairs well with almost everything, including peptides, vitamin C, and retinol. Vitamin C and vitamin E are a classic antioxidant pair, and peptides for expression lines combine well with peptides for firmness. Introduce combinations one at a time so you can see how your skin responds.
Which ingredients should I not use at the same time?
Use exfoliating acids such as glycolic or salicylic acid on different nights from retinol, because layering several strong actives can irritate skin. If your skin is sensitive, keep to one active per routine. When in doubt, alternate nights.
What are the best ingredients for mature skin?
Mature skin usually benefits from a hydrator such as hyaluronic acid, a barrier support such as ceramides or plant oils, a peptide for the look of firmness, and an antioxidant in the morning under sunscreen. Retinol or bakuchiol can be added at night once the routine is comfortable. See the firmness and hydration groups above.
How do I know which ingredients are in a product?
Check the ingredient list on the label or product page. In the U.S., ingredients are listed in descending order of predominance, with those at 1% or less allowed in any order after the others. Our glossary entries list each ingredient's INCI name so you can match it to a label.
Sources
- American Academy of Dermatology. Skin care tips dermatologists use. aad.org
- Code of Federal Regulations, 21 CFR 701.3, Designation of ingredients. ecfr.gov
- Skin Perfection usage rate decisions for serum boosters (house standard, highest manufacturer rate).
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
About the Author
Written by Kari Thomas, cosmetic formulator and founder of Skin Perfection.